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miR-29a-3p/T-bet Regulatory Circuit Is Altered in T Cells of Patients With Hashimoto’s Thyroiditis

OBJECTIVE: Hashimoto’s thyroiditis (HT) is a common autoimmune thyroid disorder that frequently evolves from asymptomatic, T-cell mediated chronic inflammation toward overt hypothyroidism. Previously, we have demonstrated a role for T-bet, a T helper 1/CD8(+) T cell transcription factor (TF), and Fo...

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Detalles Bibliográficos
Autores principales: Tokić, Stana, Štefanić, Mario, Glavaš-Obrovac, Ljubica, Kishore, Amit, Navratilova, Zdenka, Petrek, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976757/
https://www.ncbi.nlm.nih.gov/pubmed/29881372
http://dx.doi.org/10.3389/fendo.2018.00264