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Convergent Pathways in Idiopathic Autism Revealed by Time Course Transcriptomic Analysis of Patient-Derived Neurons

Potentially pathogenic alterations have been identified in individuals with autism spectrum disorders (ASDs) within a variety of key neurodevelopment genes. While this hints at a common ASD molecular etiology, gaps persist in our understanding of the neurodevelopmental mechanisms impacted by genetic...

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Detalles Bibliográficos
Autores principales: DeRosa, Brooke A., El Hokayem, Jimmy, Artimovich, Elena, Garcia-Serje, Catherine, Phillips, Andre W., Van Booven, Derek, Nestor, Jonathan E., Wang, Lily, Cuccaro, Michael L., Vance, Jeffery M., Pericak-Vance, Margaret A., Cukier, Holly N., Nestor, Michael W., Dykxhoorn, Derek M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976773/
https://www.ncbi.nlm.nih.gov/pubmed/29849033
http://dx.doi.org/10.1038/s41598-018-26495-1