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Estrogen Receptor-Alpha (ESR1) Governs the Lower Female Reproductive Tract Vulnerability to Candida albicans

Estradiol-based therapies predispose women to vaginal infections. Moreover, it has long been known that neutrophils are absent from the vaginal lumen during the ovulatory phase (high estradiol). However, the mechanisms that regulate neutrophil influx to the vagina remain unknown. We investigated the...

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Detalles Bibliográficos
Autores principales: Salinas-Muñoz, Laura, Campos-Fernández, Raúl, Mercader, Enrique, Olivera-Valle, Irene, Fernández-Pacheco, Carlota, Matilla, Lara, García-Bordas, Julio, Brazil, Jennifer C., Parkos, Charles A., Asensio, Fernando, Muñoz-Fernández, Maria A., Hidalgo, Andrés, Sánchez-Mateos, Paloma, Samaniego, Rafael, Relloso, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976782/
https://www.ncbi.nlm.nih.gov/pubmed/29881378
http://dx.doi.org/10.3389/fimmu.2018.01033