Microenvironment-Driven Dynamic Heterogeneity and Phenotypic Plasticity as a Mechanism of Melanoma Therapy Resistance

Drug resistance constitutes a major challenge in designing melanoma therapies. Microenvironment-driven tumor heterogeneity and plasticity play a key role in this phenomenon. Melanoma is highly heterogeneous with diverse genomic alterations and expression of different biological markers. In addition,...

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Detalles Bibliográficos
Autores principales: Ahmed, Farzana, Haass, Nikolas K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976798/
https://www.ncbi.nlm.nih.gov/pubmed/29881716
http://dx.doi.org/10.3389/fonc.2018.00173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976798/
https://www.ncbi.nlm.nih.gov/pubmed/29881716
http://dx.doi.org/10.3389/fonc.2018.00173

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