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Nephrolithiasis and Nephrocalcinosis From Topiramate Therapy in Children With Epilepsy

INTRODUCTION: Adults treated with topiramate may develop nephrolithiasis, but its frequency in children on topiramate is unknown. Topiramate inhibits renal carbonic anhydrase, which can lead to renal tubular acidosis and hypercalciuria. We studied 40 consecutive children who initiated topiramate the...

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Detalles Bibliográficos
Autores principales: Barnett, Sarah M., Jackson, Anthony H., Rosen, Beth A., Garb, Jane L., Braden, Gregory L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976810/
https://www.ncbi.nlm.nih.gov/pubmed/29854977
http://dx.doi.org/10.1016/j.ekir.2018.02.005