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Inhibition of Akt/mTOR/p70S6K Signaling Activity With Huangkui Capsule Alleviates the Early Glomerular Pathological Changes in Diabetic Nephropathy

Huangkui capsule (HKC), a Chinese modern patent medicine extracted from Abelmoschus manihot (L.) medic, has been widely applied to clinical therapy in the early diabetic nephropathy (DN) patients. However, it remains elusive whether HKC can ameliorate the inchoate glomerular injuries in hyperglycemi...

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Detalles Bibliográficos
Autores principales: Wu, Wei, Hu, Wei, Han, Wen-Bei, Liu, Ying-Lu, Tu, Yue, Yang, Hai-Ming, Fang, Qi-Jun, Zhou, Mo-Yi, Wan, Zi-Yue, Tang, Ren-Mao, Tang, Hai-Tao, Wan, Yi-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976825/
https://www.ncbi.nlm.nih.gov/pubmed/29881349
http://dx.doi.org/10.3389/fphar.2018.00443