Mathematical Modeling Reveals the Role of Hypoxia in the Promotion of Human Mesenchymal Stem Cell Long-Term Expansion

Many experimental studies have found that human mesenchymal stem cells (MSCs) in long-term culture exhibited enhanced cell proliferation and prolonged lifespan under hypoxia (around 1%–7% oxygen) against the normoxic condition (about 21% oxygen). Inspired by the experimental findings, we aimed to in...

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Detalles Bibliográficos
Autores principales: Gao, Shuhua, Xiang, Cheng, Qin, Kairong, Sun, Changkai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976908/
https://www.ncbi.nlm.nih.gov/pubmed/29861746
http://dx.doi.org/10.1155/2018/9283432

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976908/
https://www.ncbi.nlm.nih.gov/pubmed/29861746
http://dx.doi.org/10.1155/2018/9283432

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