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DICER1 Syndrome: DICER1 Mutations in Rare Cancers

DICER1 syndrome is a rare genetic disorder that predisposes individuals to multiple cancer types. Through mutations of the gene encoding the endoribonuclease, Dicer, DICER1 syndrome disrupts the biogenesis and processing of miRNAs with subsequent disruption in control of gene expression. Since the f...

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Detalles Bibliográficos
Autores principales: Robertson, Jake C., Jorcyk, Cheryl L., Oxford, Julia Thom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977116/
https://www.ncbi.nlm.nih.gov/pubmed/29762508
http://dx.doi.org/10.3390/cancers10050143