Eukaryotic Translation Initiation Factor 4A Down-Regulation Mediates Interleukin-24-Induced Apoptosis through Inhibition of Translation

Dysregulated activity of helicase eIF4A drives transformation to and maintenance of cancer cell phenotype by reprogramming cellular translation. Interleukin 24 (IL-24) is a tumor-suppressing protein, which has the ability to inhibit angiogenesis, sensitize cancer cells to chemotherapy, and induce ca...

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Detalles Bibliográficos
Autores principales: Zhong, Xuelin, Persaud, Leah, Muharam, Hilal, Francis, Ashleigh, Das, Dibash, Aktas, Bertal Huseyin, Sauane, Moira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977126/
https://www.ncbi.nlm.nih.gov/pubmed/29786657
http://dx.doi.org/10.3390/cancers10050153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977126/
https://www.ncbi.nlm.nih.gov/pubmed/29786657
http://dx.doi.org/10.3390/cancers10050153

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