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Hyperosmolal vaginal lubricants markedly reduce epithelial barrier properties in a three-dimensional vaginal epithelium model

Most of the widely used vaginal lubricants in the U.S. and Europe are strongly hyperosmolal, formulated with high concentrations of glycerol, propylene glycol, polyquaternary compounds or other ingredients that make these lubricants 4 to 30 times the osmolality of healthy vaginal fluid. Hyperosmolal...

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Detalles Bibliográficos
Autores principales: Ayehunie, Seyoum, Wang, Ying-Ying, Landry, Timothy, Bogojevic, Stephanie, Cone, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977164/
https://www.ncbi.nlm.nih.gov/pubmed/29854584
http://dx.doi.org/10.1016/j.toxrep.2017.12.011