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Telomere Maintenance Mechanisms in Cancer

Tumour cells can adopt telomere maintenance mechanisms (TMMs) to avoid telomere shortening, an inevitable process due to successive cell divisions. In most tumour cells, telomere length (TL) is maintained by reactivation of telomerase, while a small part acquires immortality through the telomerase-i...

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Detalles Bibliográficos
Autores principales: Bordeira Gaspar, Tiago, Sá, Ana, Lopes, José Manuel, Sobrinho-Simões, Manuel, Soares, Paula, Vinagre, João
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977181/
https://www.ncbi.nlm.nih.gov/pubmed/29751586
http://dx.doi.org/10.3390/genes9050241