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Characterization of NS5A and NS5B Resistance-Associated Substitutions from Genotype 1 Hepatitis C Virus Infected Patients in a Portuguese Cohort

This study is focused on the prevalent NS5 coding region resistance-associated substitutions (RASs) in DAA-naive genotype (GT)1 HCV-infected patients and their potential impact on success rates. Plasma RNA from 81 GT1 HCV-infected patients was extracted prior to an in-house nested RT-PCR of the NS5...

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Detalles Bibliográficos
Autores principales: Brandão, Ruben, Marcelino, Rute, Gonçalves, Fátima, Diogo, Isabel, Carvalho, Ana, Cabanas, Joaquim, Costa, Inês, Brogueira, Pedro, Ventura, Fernando, Miranda, Ana, Mansinho, Kamal, Gomes, Perpétua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977216/
https://www.ncbi.nlm.nih.gov/pubmed/29701642
http://dx.doi.org/10.3390/v10050223