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Inhibition of Human Immunodeficiency Virus Type 1 Entry by a Keggin Polyoxometalate

Here, we report the anti-human immunodeficiency virus (HIV) potency and underlying mechanisms of a Keggin polyoxometalate (PT-1, K(6)HPTi(2)W(10)O(40)). Our findings showed that PT-1 exhibited highly potent effects against a diverse group of HIV type 1 (HIV-1) strains and displayed low cytotoxicity...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoli, Wang, Jiao, Zhang, Wenmei, Li, Boye, Zhu, Ying, Hu, Qin, Yang, Yishu, Zhang, Xiaoguang, Yan, Hong, Zeng, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977258/
https://www.ncbi.nlm.nih.gov/pubmed/29772712
http://dx.doi.org/10.3390/v10050265