Heterogenic expression of stem cell markers in patient-derived glioblastoma spheroid cultures exposed to long-term hypoxia

AIM: To investigate the time profile of hypoxia and stem cell markers in glioblastoma spheroids of known molecular subtype. MATERIALS & METHODS: Patient-derived glioblastoma spheroids were cultured up to 7 days in either 2% or 21% oxygen. Levels of proliferation (Ki-67), hypoxia (HIF-1α, CA9 and...

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Detalles Bibliográficos
Autores principales: Rosenberg, Tine, Aaberg-Jessen, Charlotte, Petterson, Stine Asferg, Kristensen, Bjarne Winther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977272/
https://www.ncbi.nlm.nih.gov/pubmed/29708435
http://dx.doi.org/10.2217/cns-2017-0034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977272/
https://www.ncbi.nlm.nih.gov/pubmed/29708435
http://dx.doi.org/10.2217/cns-2017-0034

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