Cationic Liposomes Carrying siRNA: Impact of Lipid Composition on Physicochemical Properties, Cytotoxicity and Endosomal Escape

In recent year, cationic liposomes have gained a lot of attention for siRNA delivery. Despite this, intracellular barriers as endosomal escape and cytosolic delivery of siRNA still represent a challeng, as well as the cytotoxicity due to cationic lipids. To address these issues, we developed four li...

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Detalles Bibliográficos
Autores principales: Lechanteur, Anna, Sanna, Vincent, Duchemin, Amandine, Evrard, Brigitte, Mottet, Denis, Piel, Géraldine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977284/
https://www.ncbi.nlm.nih.gov/pubmed/29695068
http://dx.doi.org/10.3390/nano8050270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977284/
https://www.ncbi.nlm.nih.gov/pubmed/29695068
http://dx.doi.org/10.3390/nano8050270

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