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Aggregation of lipid rafts activates c-met and c-Src in non-small cell lung cancer cells

BACKGROUND: Activation of c-Met, a receptor tyrosine kinase, induces radiation therapy resistance in non-small cell lung cancer (NSCLC). The activated residual of c-Met is located in lipid rafts (Duhon et al. Mol Carcinog 49:739-49, 2010). Therefore, we hypothesized that disturbing the integrity of...

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Detalles Bibliográficos
Autores principales: Zeng, Juan, Zhang, Heying, Tan, Yonggang, Sun, Cheng, Liang, Yusi, Yu, Jinyang, Zou, Huawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977465/
https://www.ncbi.nlm.nih.gov/pubmed/29848294
http://dx.doi.org/10.1186/s12885-018-4501-8