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Aggregation of lipid rafts activates c-met and c-Src in non-small cell lung cancer cells

BACKGROUND: Activation of c-Met, a receptor tyrosine kinase, induces radiation therapy resistance in non-small cell lung cancer (NSCLC). The activated residual of c-Met is located in lipid rafts (Duhon et al. Mol Carcinog 49:739-49, 2010). Therefore, we hypothesized that disturbing the integrity of...

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Detalles Bibliográficos
Autores principales:	Zeng, Juan, Zhang, Heying, Tan, Yonggang, Sun, Cheng, Liang, Yusi, Yu, Jinyang, Zou, Huawei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977465/ https://www.ncbi.nlm.nih.gov/pubmed/29848294 http://dx.doi.org/10.1186/s12885-018-4501-8

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