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Improved accuracy assessment for 3D genome reconstructions
BACKGROUND: Three dimensional (3D) genome spatial organization is critical for numerous cellular functions, including transcription, while certain conformation-driven structural alterations are frequently oncogenic. Genome conformation had been difficult to elucidate but the advent chromatin conform...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977474/ https://www.ncbi.nlm.nih.gov/pubmed/29848293 http://dx.doi.org/10.1186/s12859-018-2214-2 |