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Improved accuracy assessment for 3D genome reconstructions

BACKGROUND: Three dimensional (3D) genome spatial organization is critical for numerous cellular functions, including transcription, while certain conformation-driven structural alterations are frequently oncogenic. Genome conformation had been difficult to elucidate but the advent chromatin conform...

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Detalles Bibliográficos
Autores principales:	Segal, Mark R., Bengtsson, Henrik L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977474/ https://www.ncbi.nlm.nih.gov/pubmed/29848293 http://dx.doi.org/10.1186/s12859-018-2214-2

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