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Combining photochemistry and catalysis: rapid access to sp(3) – rich polyheterocycles from simple pyrroles

Use of FEP flow reactor technology allows access to gram quantities of photochemically-generated tricyclic aziridines. These undergo a range of novel palladium-catalyzed ring-opening and cycloaddition reactions, likely driven by their inherent strain, allowing incorporation of further functionality...

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Detalles Bibliográficos
Autores principales: Blackham, Emma E., Knowles, Jonathan P., Burgess, Jonathan, Booker-Milburn, Kevin I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977501/
https://www.ncbi.nlm.nih.gov/pubmed/29910920
http://dx.doi.org/10.1039/c5sc04062k