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Integrative analysis of DNA methylation and gene expression reveals hepatocellular carcinoma-specific diagnostic biomarkers

BACKGROUND: Hepatocellular carcinoma (HCC) is the one of the most common cancers and lethal diseases in the world. DNA methylation alteration is frequently observed in HCC and may play important roles in carcinogenesis and diagnosis. METHODS: Using the TCGA HCC dataset, we classified HCC patients in...

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Detalles Bibliográficos
Autores principales: Cheng, Jinming, Wei, Dongkai, Ji, Yuan, Chen, Lingli, Yang, Liguang, Li, Guang, Wu, Leilei, Hou, Ting, Xie, Lu, Ding, Guohui, Li, Hong, Li, Yixue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977535/
https://www.ncbi.nlm.nih.gov/pubmed/29848370
http://dx.doi.org/10.1186/s13073-018-0548-z