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Impact of the biological definition of Alzheimer’s disease using amyloid, tau and neurodegeneration (ATN): what about the role of vascular changes, inflammation, Lewy body pathology?

BACKGROUND: The NIA-AA research framework proposes a biological definition of Alzheimer’s disease, where asymptomatic persons with amyloid deposition would be considered as having this disease prior to symptoms. DISCUSSION: Notwithstanding the fact that amyloid deposition in isolation is not associa...

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Detalles Bibliográficos
Autores principales: Gauthier, S., Zhang, H., Ng, K. P., Pascoal, T.A., Rosa-Neto, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977549/
https://www.ncbi.nlm.nih.gov/pubmed/29876101
http://dx.doi.org/10.1186/s40035-018-0117-9