Cargando…

NUP155 insufficiency recalibrates a pluripotent transcriptome with network remodeling of a cardiogenic signaling module

BACKGROUND: Atrial fibrillation is a cardiac disease driven by numerous idiopathic etiologies. NUP155 is a nuclear pore complex protein that has been identified as a clinical driver of atrial fibrillation, yet the precise mechanism is unknown. The present study employs a systems biology algorithm to...

Descripción completa

Detalles Bibliográficos
Autores principales: Preston, Claudia C., Wyles, Saranya P., Reyes, Santiago, Storm, Emily C., Eckloff, Bruce W., Faustino, Randolph S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977756/
https://www.ncbi.nlm.nih.gov/pubmed/29848314
http://dx.doi.org/10.1186/s12918-018-0590-x