Cargando…
NUP155 insufficiency recalibrates a pluripotent transcriptome with network remodeling of a cardiogenic signaling module
BACKGROUND: Atrial fibrillation is a cardiac disease driven by numerous idiopathic etiologies. NUP155 is a nuclear pore complex protein that has been identified as a clinical driver of atrial fibrillation, yet the precise mechanism is unknown. The present study employs a systems biology algorithm to...
Autores principales: | Preston, Claudia C., Wyles, Saranya P., Reyes, Santiago, Storm, Emily C., Eckloff, Bruce W., Faustino, Randolph S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977756/ https://www.ncbi.nlm.nih.gov/pubmed/29848314 http://dx.doi.org/10.1186/s12918-018-0590-x |
Ejemplares similares
-
Protein Subdomain Enrichment of NUP155 Variants Identify a Novel Predicted Pathogenic Hotspot
por: Leonard, Riley J., et al.
Publicado: (2020) -
Corrigendum: Protein Subdomain Enrichment of NUP155 Variants Identify a Novel Predicted Pathogenic Hotspot
por: Leonard, Riley J., et al.
Publicado: (2020) -
Nucleoporin insufficiency disrupts a pluripotent regulatory circuit in a pro-arrhythmogenic stem cell line
por: Preston, Claudia C., et al.
Publicado: (2019) -
Systems biology surveillance decrypts pathological transcriptome remodeling
por: Faustino, Randolph S., et al.
Publicado: (2015) -
Specific Binding of the Karyopherin Kap121p to a Subunit of the Nuclear Pore Complex Containing Nup53p, Nup59p, and Nup170p
por: Marelli, Marcello, et al.
Publicado: (1998)