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Integrin α(D)β(2) (CD11d/CD18) Modulates Leukocyte Accumulation, Pathogen Clearance, and Pyroptosis in Experimental Salmonella Typhimurium Infection

β(2) integrins are critical in host defense responses to invading pathogens and inflammation. Previously, we reported that genetic deficiency of integrin α(D)β(2) in mice altered outcomes in experimental systemic infections including accelerated mortality in animals infected with Salmonella enterica...

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Detalles Bibliográficos
Autores principales: Nascimento, Danielle de Oliveira, Vieira-de-Abreu, Adriana, Arcanjo, Angélica F., Bozza, Patricia Torres, Zimmerman, Guy A., Castro-Faria-Neto, Hugo Caire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977906/
https://www.ncbi.nlm.nih.gov/pubmed/29881383
http://dx.doi.org/10.3389/fimmu.2018.01128