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Targeting PIM kinase as a therapeutic strategy in human hepatoblastoma

Increasing incidence coupled with poor prognosis and treatments that are virtually unchanged over the past 20 years have made the need for the development of novel therapeutics for hepatoblastoma imperative. PIM kinases have been implicated as drivers of tumorigenesis in multiple cancers, including...

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Detalles Bibliográficos
Autores principales: Stafman, Laura L., Mruthyunjayappa, Smitha, Waters, Alicia M., Garner, Evan F., Aye, Jamie M., Stewart, Jerry E., Yoon, Karina J., Whelan, Kimberly, Mroczek-Musulman, Elizabeth, Beierle, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978256/
https://www.ncbi.nlm.nih.gov/pubmed/29854306
http://dx.doi.org/10.18632/oncotarget.25205