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Effect of the monoclonal antibody TRC105 in combination with Sunitinib on renal tumor derived endothelial cells
Anti-angiogenic therapy is an important strategy to limit growth, development and expansion of solid tumors. However, resistance to VEGF-targeting agents may develop, due to activation of alternative pro-angiogenic pathways, indicating the need of multiple target strategy. Here we obtained tumor end...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978257/ https://www.ncbi.nlm.nih.gov/pubmed/29854307 http://dx.doi.org/10.18632/oncotarget.25206 |