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Architecture of a channel-forming O-antigen polysaccharide ABC transporter

O-antigens are cell surface polysaccharides of many Gram-negative pathogens that aid in escaping innate immune responses.(1) A widespread O-antigen biosynthesis mechanism involves the synthesis of the lipid-anchored polymer on the inner membrane’s (IM’s) cytosolic face, followed by transport to the...

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Detalles Bibliográficos
Autores principales: Bi, Yunchen, Mann, Evan, Whitfield, Chris, Zimmer, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978415/
https://www.ncbi.nlm.nih.gov/pubmed/29320481
http://dx.doi.org/10.1038/nature25190