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C9orf140, a novel Axin1-interacting protein, mediates the negative feedback loop of Wnt/β-catenin signaling

Wnt/β-catenin signaling activity is maintained in homeostasis by an expanding list of molecular determinants. However, the molecular components and the regulatory mechanisms involved in its fine-tuning remain to be determined. Here, we identified C9orf140, a tumor-specific protein, as a novel Axin1-...

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Detalles Bibliográficos
Autores principales: Jiang, Jun, Tang, Shulin, Xia, Jianhong, Wen, Jikai, Chen, Shuang, Shu, Xiaodong, Huen, Michael S. Y., Deng, Yiqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978805/
https://www.ncbi.nlm.nih.gov/pubmed/29531269
http://dx.doi.org/10.1038/s41388-018-0166-7