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The landscape of genetic alterations in ameloblastomas relates to clinical features

Ameloblastoma is a mostly benign, but locally invasive odontogenic tumor eliciting frequent relapses and significant morbidity. Recently, mutually exclusive mutations in BRAF and SMO were identified causing constitutive activation of MAPK and hedgehog signaling pathways. To explore further such clin...

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Detalles Bibliográficos
Autores principales: Gültekin, Sibel Elif, Aziz, Reem, Heydt, Carina, Sengüven, Burcu, Zöller, Joachim, Safi, Ali Farid, Kreppel, Matthias, Buettner, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978850/
https://www.ncbi.nlm.nih.gov/pubmed/29388014
http://dx.doi.org/10.1007/s00428-018-2305-5