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Dissection of the antimicrobial and hemolytic activity of Cap18: Generation of Cap18 derivatives with enhanced specificity

Due to the rapid emergence of resistance to classical antibiotics, novel antimicrobial compounds are needed. It is desirable to selectively kill pathogenic bacteria without targeting other beneficial bacteria in order to prevent the negative clinical consequences caused by many broad-spectrum antibi...

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Detalles Bibliográficos
Autores principales: Ebbensgaard, Anna, Mordhorst, Hanne, Overgaard, Michael Toft, Aarestrup, Frank Møller, Hansen, Egon Bech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978884/
https://www.ncbi.nlm.nih.gov/pubmed/29852015
http://dx.doi.org/10.1371/journal.pone.0197742