Lack of human-like extracellular sortilin neuropathology in transgenic Alzheimer’s disease model mice and macaques

BACKGROUND: Alzheimer’s disease (AD) is a devastating neurodegenerative disorder bearing multiple pathological hallmarks suggestive of complex cellular/molecular interplay during pathogenesis. Transgenic mice and nonhuman primates are used as disease models for mechanistic and translational research...

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Detalles Bibliográficos
Autores principales: Zhou, Feng-Qin, Jiang, Juan, Griffith, Chelsea M., Patrylo, Peter R., Cai, Huaibin, Chu, Yaping, Yan, Xiao-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978992/
https://www.ncbi.nlm.nih.gov/pubmed/29690919
http://dx.doi.org/10.1186/s13195-018-0370-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978992/
https://www.ncbi.nlm.nih.gov/pubmed/29690919
http://dx.doi.org/10.1186/s13195-018-0370-2

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