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Lack of human-like extracellular sortilin neuropathology in transgenic Alzheimer’s disease model mice and macaques

BACKGROUND: Alzheimer’s disease (AD) is a devastating neurodegenerative disorder bearing multiple pathological hallmarks suggestive of complex cellular/molecular interplay during pathogenesis. Transgenic mice and nonhuman primates are used as disease models for mechanistic and translational research...

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Detalles Bibliográficos
Autores principales:	Zhou, Feng-Qin, Jiang, Juan, Griffith, Chelsea M., Patrylo, Peter R., Cai, Huaibin, Chu, Yaping, Yan, Xiao-Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978992/ https://www.ncbi.nlm.nih.gov/pubmed/29690919 http://dx.doi.org/10.1186/s13195-018-0370-2

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