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Serum of myeloproliferative neoplasms stimulates hematopoietic stem and progenitor cells

BACKGROUND: Myeloproliferative neoplasms (MPN)—such as polycythemia vera (PV), essential thrombocythemia (ET), and myelofibrosis (MF)—are typically diseases of the elderly caused by acquired somatic mutations. However, it is largely unknown how the malignant clone interferes with normal hematopoiesi...

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Detalles Bibliográficos
Autores principales: Lubberich, Richard K., Walenda, Thomas, Goecke, Tamme W., Strathmann, Klaus, Isfort, Susanne, Brümmendorf, Tim H., Koschmieder, Steffen, Wagner, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979002/
https://www.ncbi.nlm.nih.gov/pubmed/29851963
http://dx.doi.org/10.1371/journal.pone.0197233