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A Developed NK-92MI Cell Line with Siglec-7(neg) Phenotype Exhibits High and Sustainable Cytotoxicity against Leukemia Cells

Altered sialic acid processing that leads to upregulation of cell surface sialylation is recognized as a key change in malignant tissue glycosylation. This cancer-associated hypersialylation directly impacts the signaling interactions between tumor cells and their surrounding microenvironment, espec...

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Detalles Bibliográficos
Autores principales: Huang, Chin-Han, Liao, Yi-Jen, Fan, Ting-Hsi, Chiou, Tzeon-Jye, Lin, Yen-Hsi, Twu, Yuh-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979288/
https://www.ncbi.nlm.nih.gov/pubmed/29617289
http://dx.doi.org/10.3390/ijms19041073