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Testosterone-Dependent miR-26a-5p and let-7g-5p Act as Signaling Mediators to Regulate Sperm Apoptosis via Targeting PTEN and PMAIP1

Recent evidence suggests that testosterone deficiency can dramatically decrease the quality of sperm. MicroRNAs (miRNAs) are conserved mediators of post-transcriptional gene regulation in eukaryotes. However, the systemic regulation and function of miRNAs in sperm quality decline induced by testoste...

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Detalles Bibliográficos
Autores principales: Ma, Jideng, Fan, Yu, Zhang, Jinwei, Feng, Siyuan, Hu, Zihui, Qiu, Wanling, Long, Keren, Jin, Long, Tang, Qianzi, Wang, Xun, Zhou, Qi, Gu, Yiren, Xiao, Weihang, Liu, Lingyan, Li, Xuewei, Li, Mingzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979296/
https://www.ncbi.nlm.nih.gov/pubmed/29670053
http://dx.doi.org/10.3390/ijms19041233