Prenatal Metformin Therapy Attenuates Hypertension of Developmental Origin in Male Adult Offspring Exposed to Maternal High-Fructose and Post-Weaning High-Fat Diets

Widespread consumption of a Western diet, comprised of highly refined carbohydrates and fat, may play a role in the epidemic of hypertension. Hypertension can take origin from early life. Metformin is the preferred treatment for type 2 diabetes. We examined whether prenatal metformin therapy can pre...

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Detalles Bibliográficos
Autores principales: Tain, You-Lin, Wu, Kay L. H., Lee, Wei-Chia, Leu, Steve, Chan, Julie Y. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979307/
https://www.ncbi.nlm.nih.gov/pubmed/29614026
http://dx.doi.org/10.3390/ijms19041066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979307/
https://www.ncbi.nlm.nih.gov/pubmed/29614026
http://dx.doi.org/10.3390/ijms19041066

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