Brca1 Is Upregulated by 5-Aza-CdR and Promotes DNA Repair and Cell Survival, and Inhibits Neurite Outgrowth in Rat Retinal Neurons

Previous studies have reported that Brca1 acts as a “hinge” in the development of the central nervous system (CNS). However, the precise role of Brca1 in rat retinal neurons remains unclear. Here, we found that Brca1 is developmentally downregulated and silenced in adult retina. Brca1 was upregulate...

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Detalles Bibliográficos
Autores principales: Wang, Qiyun, Xu, Lijun, Chen, Pei, Xu, Zhuojun, Qiu, Jin, Ge, Jian, Yu, Keming, Zhuang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979323/
https://www.ncbi.nlm.nih.gov/pubmed/29673145
http://dx.doi.org/10.3390/ijms19041214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979323/
https://www.ncbi.nlm.nih.gov/pubmed/29673145
http://dx.doi.org/10.3390/ijms19041214

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