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Brca1 Is Upregulated by 5-Aza-CdR and Promotes DNA Repair and Cell Survival, and Inhibits Neurite Outgrowth in Rat Retinal Neurons
Previous studies have reported that Brca1 acts as a “hinge” in the development of the central nervous system (CNS). However, the precise role of Brca1 in rat retinal neurons remains unclear. Here, we found that Brca1 is developmentally downregulated and silenced in adult retina. Brca1 was upregulate...
Autores principales: | Wang, Qiyun, Xu, Lijun, Chen, Pei, Xu, Zhuojun, Qiu, Jin, Ge, Jian, Yu, Keming, Zhuang, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979323/ https://www.ncbi.nlm.nih.gov/pubmed/29673145 http://dx.doi.org/10.3390/ijms19041214 |
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