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Erythropoietin Intensifies the Proapoptotic Activity of LFM-A13 in Cells and in a Mouse Model of Colorectal Cancer

The Bruton’s tyrosine kinase (BTK) inhibitor LFM-A13 has been widely employed as an antileukemic agent, but applications in solid cancer have been found recently. The compound promotes apoptosis, has an antiproliferative effect, and increases cancer cell sensitivity to chemotherapy drugs. We decided...

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Detalles Bibliográficos
Autores principales: Tankiewicz-Kwedlo, Anna, Hermanowicz, Justyna Magdalena, Pawlak, Krystyna, Czarnomysy, Robert, Bielawski, Krzysztof, Prokop, Izabela, Pawlak, Dariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979332/
https://www.ncbi.nlm.nih.gov/pubmed/29690619
http://dx.doi.org/10.3390/ijms19041262