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NF2/Merlin Inactivation and Potential Therapeutic Targets in Mesothelioma
The neurofibromatosis type 2 (NF2) gene encodes merlin, a tumor suppressor protein frequently inactivated in schwannoma, meningioma, and malignant mesothelioma (MM). The sequence of merlin is similar to that of ezrin/radixin/moesin (ERM) proteins which crosslink actin with the plasma membrane, sugge...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979333/ https://www.ncbi.nlm.nih.gov/pubmed/29587439 http://dx.doi.org/10.3390/ijms19040988 |