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Angiotensin II-Induced Mesangial Cell Damage Is Preceded by Cell Membrane Permeabilization Due to Upregulation of Non-Selective Channels

Connexin43 (Cx43), pannexin1 (Panx1) and P2X(7) receptor (P2X(7)R) are expressed in kidneys and are known to constitute a feedforward mechanism leading to inflammation in other tissues. However, the possible functional relationship between these membrane channels and their role in damaged renal cell...

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Detalles Bibliográficos
Autores principales: Gómez, Gonzalo I., Fernández, Paola, Velarde, Victoria, Sáez, Juan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979336/
https://www.ncbi.nlm.nih.gov/pubmed/29570626
http://dx.doi.org/10.3390/ijms19040957