Opposing Roles of Calcium and Intracellular ATP on Gating of the Purinergic P2X2 Receptor Channel

P2X2 receptors (P2X2R) exhibit a slow desensitization during the initial ATP application and a progressive, calcium-dependent increase in rates of desensitization during repetitive stimulation. This pattern is observed in whole-cell recordings from cells expressing recombinant and native P2X2R. Howe...

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Detalles Bibliográficos
Autores principales: Rokic, Milos B., Castro, Patricio, Leiva-Salcedo, Elias, Tomic, Melanija, Stojilkovic, Stanko S., Coddou, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979340/
https://www.ncbi.nlm.nih.gov/pubmed/29641486
http://dx.doi.org/10.3390/ijms19041161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979340/
https://www.ncbi.nlm.nih.gov/pubmed/29641486
http://dx.doi.org/10.3390/ijms19041161

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