Cargando…

Opposing Roles of Calcium and Intracellular ATP on Gating of the Purinergic P2X2 Receptor Channel

P2X2 receptors (P2X2R) exhibit a slow desensitization during the initial ATP application and a progressive, calcium-dependent increase in rates of desensitization during repetitive stimulation. This pattern is observed in whole-cell recordings from cells expressing recombinant and native P2X2R. Howe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rokic, Milos B., Castro, Patricio, Leiva-Salcedo, Elias, Tomic, Melanija, Stojilkovic, Stanko S., Coddou, Claudio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979340/ https://www.ncbi.nlm.nih.gov/pubmed/29641486 http://dx.doi.org/10.3390/ijms19041161

Ejemplares similares

Gating properties of the P2X2a and P2X2b receptor channels: Experiments and mathematical modeling
por: Khadra, Anmar, et al.
Publicado: (2012)

Structural and functional properties of the rat P2X4 purinoreceptor extracellular vestibule during gating
por: Rokic, Milos B., et al.
Publicado: (2014)

Release and extracellular metabolism of ATP by ecto-nucleotidase eNTPDase 1–2 in hypothalamic and pituitary cells
por: He, Mu-Lan, et al.
Publicado: (2005)

Two open states of P2X receptor channels
por: Rokic, Milos B., et al.
Publicado: (2013)

Paliperidone and aripiprazole differentially affect the strength of calcium-secretion coupling in female pituitary lactotrophs
por: Kucka, Marek, et al.
Publicado: (2015)

The P2X(7) Receptor Channel Pore Dilates under Physiological Ion Conditions
por: Yan, Zonghe, et al.
Publicado: (2008)

The Role of Cyclic Nucleotides in Pituitary Lactotroph Functions
por: Kucka, Marek, et al.
Publicado: (2013)

Identification of Functionally Important Residues of the Rat P2X4 Receptor by Alanine Scanning Mutagenesis of the Dorsal Fin and Left Flipper Domains
por: Tvrdonova, Vendula, et al.
Publicado: (2014)

Multiple Roles of the Extracellular Vestibule Amino Acid Residues in the Function of the Rat P2X4 Receptor
por: Rokic, Milos B., et al.
Publicado: (2013)

Calcium-Prolactin Secretion Coupling in Rat Pituitary Lactotrophs Is Controlled by PI4-Kinase Alpha
por: Kučka, Marek, et al.
Publicado: (2021)

Regulation of ClC-2 gating by intracellular ATP
por: Stölting, Gabriel, et al.
Publicado: (2013)

GnRH Induces ERK-Dependent Bleb Formation in Gonadotrope Cells, Involving Recruitment of Members of a GnRH Receptor-Associated Signalosome to the Blebs
por: Rahamim-Ben Navi, Liat, et al.
Publicado: (2017)

Purinergic Signaling and Aminoglycoside Ototoxicity: The Opposing Roles of P1 (Adenosine) and P2 (ATP) Receptors on Cochlear Hair Cell Survival
por: Lin, Shelly C. Y., et al.
Publicado: (2019)

Deciphering the regulation of P2X4 receptor channel gating by ivermectin using Markov models
por: Mackay, Laurent, et al.
Publicado: (2017)

Calcium-dependent block of P2X7 receptor channel function is allosteric
por: Yan, Zonghe, et al.
Publicado: (2011)

Divalent metal modulation of Japanese flounder (Paralichthys olivaceus) purinergic P2X7 receptor
por: Paredes, Carolina, et al.
Publicado: (2018)

Implications of purinergic receptor-mediated intracellular calcium transients in neural differentiation
por: Glaser, Talita, et al.
Publicado: (2013)

Cell Type- and Sex-Dependent Transcriptome Profiles of Rat Anterior Pituitary Cells
por: Fletcher, Patrick A., et al.
Publicado: (2019)

Molecular Characterization and Expression Analysis of ATP-Gated P2X7 Receptor Involved in Japanese Flounder (Paralichthys olivaceus) Innate Immune Response
por: Li, Shuo, et al.
Publicado: (2014)

PI(4,5)P2-dependent and -independent roles of PI4P in the control of hormone secretion by pituitary cells
por: Stojilkovic, Stanko S., et al.
Publicado: (2023)

Differential Effects of Purinergic Signaling in Gastric Cancer-Derived Cells Through P2Y and P2X Receptors
por: Hevia, María José, et al.
Publicado: (2019)

Organization of ATP-gated P2X1 receptor intracellular termini in apo and desensitized states
por: Fryatt, Alistair G., et al.
Publicado: (2019)

ATP release and purinergic signaling in NLRP3 inflammasome activation
por: Gombault, Aurélie, et al.
Publicado: (2013)

Colligative Property of ATP: Implications for Enteric Purinergic Neuromuscular Neurotransmission
por: Chaudhury, Arun, et al.
Publicado: (2016)

Extracellular ATP acts on P2Y2 purinergic receptors to facilitate HIV-1 infection
por: Séror, Claire, et al.
Publicado: (2011)

Ionotropic P2X ATP Receptor Channels Mediate Purinergic Signaling in Mouse Odontoblasts
por: Shiozaki, Yuta, et al.
Publicado: (2017)

Voltage- and [ATP]-dependent Gating of the P2X(2) ATP Receptor Channel
por: Fujiwara, Yuichiro, et al.
Publicado: (2009)

Purinergic and Calcium Signaling in Macrophage Function and Plasticity
por: Desai, Bimal N., et al.
Publicado: (2014)

Purinergic Calcium Signals in Tumor-Derived Endothelium
por: Scarpellino, Giorgia, et al.
Publicado: (2019)

Purinergic Signaling of ATP in COVID-19 Associated Guillain-Barré Syndrome
por: Simões, Júlia Leão Batista, et al.
Publicado: (2021)

Sirtuin 6 Regulates the Activation of the ATP/Purinergic Axis in Endothelial Cells
por: Astigiano, Cecilia, et al.
Publicado: (2023)

Purinergic P2Y2 and P2X4 Receptors Are Involved in the Epithelial-Mesenchymal Transition and Metastatic Potential of Gastric Cancer Derived Cell Lines
por: Reyna-Jeldes, Mauricio, et al.
Publicado: (2021)

Simultaneous Fluorescent Recordings of Extracellular ATP and IntracellularCalcium in Mammalian Cells
por: Mikolajewicz, Nicholas, et al.
Publicado: (2019)

Trimethylamine N-Oxide (TMAO) Impairs Purinergic Induced Intracellular Calcium Increase and Nitric Oxide Release in Endothelial Cells
por: Querio, Giulia, et al.
Publicado: (2022)

Identification of a distinct desensitisation gate in the ATP-gated P2X2 receptor
por: Stavrou, Anastasios, et al.
Publicado: (2020)

Effect of the Purinergic Inhibitor Oxidized ATP in a Model of Islet Allograft Rejection
por: Vergani, Andrea, et al.
Publicado: (2013)

Purinergic and muscarinic modulation of ATP release from the urothelium and its paracrine actions
por: Sui, Guiping, et al.
Publicado: (2013)

Purinergic receptor mediated calcium signalling in urothelial cells
por: Chess-Williams, Russell, et al.
Publicado: (2019)

The Intracellular Amino Terminus Plays a Dominant Role in Desensitization of ATP-gated P2X Receptor Ion Channels
por: Allsopp, Rebecca C., et al.
Publicado: (2011)

Contribution of the Juxtatransmembrane Intracellular Regions to the Time Course and Permeation of ATP-gated P2X7 Receptor Ion Channels
por: Allsopp, Rebecca C., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_a71cprikr76iilb8jdairf80j7