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The Recombinant Inhibitor of DNA Binding Id2 Forms Multimeric Structures via the Helix-Loop-Helix Domain and the Nuclear Export Signal

The inhibitor of DNA binding and cell differentiation 2 (Id2) is a helix-loop-helix (HLH) protein that acts as negative dominant regulator of basic-HLH transcription factors during development and in cancer. The structural properties of Id2 have been investigated so far by using synthetic or recombi...

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Detalles Bibliográficos
Autores principales: Roschger, Cornelia, Schubert, Mario, Regl, Christof, Andosch, Ancuela, Marquez, Augusto, Berger, Thomas, Huber, Christian G., Lütz-Meindl, Ursula, Cabrele, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979349/
https://www.ncbi.nlm.nih.gov/pubmed/29642431
http://dx.doi.org/10.3390/ijms19041105