Excessive Extracellular ATP Desensitizes P2Y2 and P2X4 ATP Receptors Provoking Surfactant Impairment Ending in Ventilation-Induced Lung Injury

Stretching the alveolar epithelial type I (AT I) cells controls the intercellular signaling for the exocytosis of surfactant by the AT II cells through the extracellular release of adenosine triphosphate (ATP) (purinergic signaling). Extracellular ATP is cleared by extracellular ATPases, maintaining...

Descripción completa

Detalles Bibliográficos
Autores principales: Hasan, Djo, Satalin, Joshua, van der Zee, Philip, Kollisch-Singule, Michaela, Blankman, Paul, Shono, Atsuko, Somhorst, Peter, den Uil, Corstiaan, Meeder, Han, Kotani, Toru, Nieman, Gary F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979391/
https://www.ncbi.nlm.nih.gov/pubmed/29652806
http://dx.doi.org/10.3390/ijms19041185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979391/
https://www.ncbi.nlm.nih.gov/pubmed/29652806
http://dx.doi.org/10.3390/ijms19041185

Ejemplares similares