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A Single Dose of Atorvastatin Applied Acutely after Spinal Cord Injury Suppresses Inflammation, Apoptosis, and Promotes Axon Outgrowth, Which Might Be Essential for Favorable Functional Outcome

The aim of our study was to limit the inflammatory response after a spinal cord injury (SCI) using Atorvastatin (ATR), a potent inhibitor of cholesterol biosynthesis. Adult Wistar rats were divided into five experimental groups: one control group, two Th9 compression (40 g/15 min) groups, and two Th...

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Detalles Bibliográficos
Autores principales: Bimbova, Katarina, Bacova, Maria, Kisucka, Alexandra, Pavel, Jaroslav, Galik, Jan, Zavacky, Peter, Marsala, Martin, Stropkovska, Andrea, Fedorova, Jana, Papcunova, Stefania, Jachova, Jana, Lukacova, Nadezda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979414/
https://www.ncbi.nlm.nih.gov/pubmed/29642434
http://dx.doi.org/10.3390/ijms19041106