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The JAK2 GGCC (46/1) Haplotype in Myeloproliferative Neoplasms: Causal or Random?
The germline JAK2 haplotype known as “GGCC or 46/1 haplotype” (haplotype(GGCC_46/1)) consists of a combination of single nucleotide polymorphisms (SNPs) mapping in a region of about 250 kb, extending from the JAK2 intron 10 to the Insulin-like 4 (INLS4) gene. Four main SNPs (rs3780367, rs10974944, r...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979434/ https://www.ncbi.nlm.nih.gov/pubmed/29641446 http://dx.doi.org/10.3390/ijms19041152 |