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Bone Cell Activity in Clinical Prostate Cancer Bone Metastasis and Its Inverse Relation to Tumor Cell Androgen Receptor Activity

Advanced prostate cancer frequently metastasizes to bone and induces a mixed osteoblastic/osteolytic bone response. Standard treatment for metastatic prostate cancer is androgen-deprivation therapy (ADT) that also affects bone biology. Treatment options for patients relapsing after ADT are limited,...

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Detalles Bibliográficos
Autores principales: Nordstrand, Annika, Bovinder Ylitalo, Erik, Thysell, Elin, Jernberg, Emma, Crnalic, Sead, Widmark, Anders, Bergh, Anders, Lerner, Ulf H., Wikström, Pernilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979457/
https://www.ncbi.nlm.nih.gov/pubmed/29670000
http://dx.doi.org/10.3390/ijms19041223