PON-tstab: Protein Variant Stability Predictor. Importance of Training Data Quality

Several methods have been developed to predict effects of amino acid substitutions on protein stability. Benchmark datasets are essential for method training and testing and have numerous requirements including that the data is representative for the investigated phenomenon. Available machine learni...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Urolagin, Siddhaling, Niroula, Abhishek, Ding, Xuesong, Shen, Bairong, Vihinen, Mauno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979465/
https://www.ncbi.nlm.nih.gov/pubmed/29597263
http://dx.doi.org/10.3390/ijms19041009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979465/
https://www.ncbi.nlm.nih.gov/pubmed/29597263
http://dx.doi.org/10.3390/ijms19041009

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